Publications

Hahn T, Ernsting J, Winter NR, Holstein V, Leenings R, Beisemann M, Fisch L, Sarink K, Emden D, Opel N, Redlich R, Repple J, Grotegerd D, Meinert S, Hirsch JG, Niendorf T, Endemann B, Bamberg F, Kröncke T, Bülow R, Völzke H, von Stackelberg O, Sowade RF, Umutlu L, Schmidt B, Caspers S, Kugel H, Kircher T, Risse B, Gaser C, Cole JH, Dannlowski U, Berger K.
An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Sci Adv. 2022 8(1):eabg9471. PDF

Luders E, Gaser C, Gingnell M, Engman J, Sundström Poromaa I, Kurth F.
Postpartum Gray Matter Changes in the Auditory Cortex.
J Clin Med. 2021 10(23):5616. PDF

Broessner G, Ellerbrock I, Menz MM, Frank F, Verius M, Gaser C, May A.
Repetitive T1 Imaging Influences Gray Matter Volume Estimations in Structural Brain Imaging.
Front Neurol. 2021 12:755749. PDF

Kirschner M, Hodzic-Santor B, Antoniades M, Nenadic I, Kircher T, Krug A, Meller T, Grotegerd D, Fornito A, Arnatkeviciute A, Bellgrove MA, Tiego J, Dannlowski U, Koch K, Hülsmann C, Kugel H, Enneking V, Klug M, Leehr EJ, Böhnlein J, Gruber M, Mehler D, DeRosse P, Moyett A, Baune BT, Green M, Quidé Y, Pantelis C, Chan R, Wang Y, Ettinger U, Debbané M, Derome M, Gaser C, Besteher B, Diederen K, Spencer TJ, Fletcher P, Rössler W, Smigielski L, Kumari V, Premkumar P, Park HRP, Wiebels K, Lemmers-Jansen I, Gilleen J, Allen P, Kozhuharova P, Marsman JB, Lebedeva I, Tomyshev A, Mukhorina A, Kaiser S, Fett AK, Sommer I, Schuite-Koops S, Paquola C, Larivière S, Bernhardt B, Dagher A, Grant P, van Erp TGM, Turner JA, Thompson PM, Aleman A, Modinos G.
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.
Mol Psychiatry. in press. PDF

Cherbuin N, Walsh EI, Shaw M, Luders E, Anstey KJ, Sachdev PS, Abhayaratna WP, Gaser C.
Optimal Blood Pressure Keeps Our Brains Younger.
Front Aging Neurosci. 2021 13:694982. PDF

Bussas M, Grahl S, Pongratz V, Berthele A, Gasperi C, Andlauer T, Gaser C, Kirschke JS, Wiestler B, Zimmer C, Hemmer B, Mühlau M.
Gray matter atrophy in relapsing-remitting multiple sclerosis is associated with white matter lesions in connecting fibers.
Mult Scler. in press. PDF

Schmitz-Koep B, Haller B, Coupé P, Menegaux A, Gaser C, Zimmer C, Wolke D, Bartmann P, Sorg C, Hedderich DM.
Grey and White Matter Volume Changes after Preterm Birth: A Meta-Analytic Approach.
J Pers Med. 2021 11(9):868. PDF

Grahl S, Bussas M, Wiestler B, Eichinger P, Gaser C, Kirschke J, Zimmer C, Berthele A, Hemmer B, Mühlau M.
Differential Effects of Fingolimod and Natalizumab on Magnetic Resonance Imaging Measures in Relapsing-Remitting Multiple Sclerosis.
Neurotherapeutics. in press. PDF

Sevinc G, Rusche J, Wong B, Datta T, Kaufman R, Gutz SE, Schneider M, Todorova N, Gaser C, Thomalla G, Rentz D, Dickerson BD, Lazar SW.
Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults.
Front Aging Neurosci. 2021 13:702796. PDF

Fisch L, Leenings R, Winter NR, Dannlowski U, Gaser C, Cole JH, Hahn T.
Editorial: Predicting Chronological Age From Structural Neuroimaging: The Predictive Analytics Competition 2019.
Front. Psychiatry. 2021 12:710932 PDF

Martins M, Reis AM, Castro SL, Gaser C.
Gray matter correlates of reading fluency deficits: SES matters, IQ does not.
Brain Struct Funct. 2021 226(8):2585-2601 PDF

Nenadic I, Lorenz C, Gaser C.
Narcissistic personality traits and prefrontal brain structure.
Sci. Rep. 2021 11(1):15707 PDF

Evermann U, Gaser C, Meller T, Pfarr JK, Grezellschak S, Nenadic I.
Nonclinical psychotic-like experiences and schizotypy dimensions: Associations with hippocampal subfield and amygdala volumes.
Hum Brain Mapp. 2021 42(15):5075-5088 PDF

Luders E, Gaser C, Gingnell M, Engman J, Sundström Poromaa I, Kurth F.
Significant increases of the amygdala between immediate and late postpartum: Pronounced effects within the superficial subregion.
J Neurosci Res. 2021 99(9):2261-2270 PDF

Steinbach R, Prell T, Gaur N, Roediger A, Gaser C, Mayer TE, Witte OW, Grosskreutz J.
Patterns of grey and white matter changes differ between bulbar and limb onset amyotrophic lateral sclerosis.
Neuroimage Clin. 2021 30:102674 PDF

Luders E, Gaser C, Gingnell M, Engman J, Sundström Poromaa I, Kurth F.
Gray matter increases within subregions of the hippocampal complex after pregnancy.
Brain Imaging Behav. 2021 15:2790-2794 PDF

Hedderich DM, Menegaux A, Schmitz-Koep B, Nuttall R, Zimmermann J, Schneider SC, Bäuml JG, Daamen M, Boecker H, Wilke M, Zimmer C, Wolke D, Bartmann P, Sorg C, Gaser C.
Increased Brain Age Gap Estimate (BrainAGE) in Young Adults After Premature Birth.
Front Aging Neurosci. 2021 13:653365 PDF

Jamalabadi H, Zuberer A, Kumar VJ, Li M, Alizadeh S, Amani AM, Gaser C, Esterman M, Walter M.
The missing role of gray matter in studying brain controllability.
Netw Neurosci. 2021 5(1):198-210 PDF

Delvecchio G, Maggioni E, Pigoni A, Crespo-Facorro B, Nenadic I, Benedetti F, Gaser C, Sauer H, Roiz-Santiañez R, Poletti S, Rossetti MG, Bellani M, Perlini C, Ruggeri M, Diwadkar VA, Brambilla P.
Sexual Regional Dimorphism of Post-Adolescent and Middle Age Brain Maturation. A Multi-center 3T MRI Study.
Front Aging Neurosci. 2021 13:622054 PDF

Bittner N, Jockwitz C, Franke K, Gaser C, Moebus S, Bayen UJ, Amunts K, Caspers S.
When your brain looks older than expected: combined lifestyle risk and BrainAGE.
Brain Struct Funct. 2021 226(3):621-645 PDF

Schmitt S, Besteher B, Gaser C, Nenadic I.
Human time perspective and its structural associations with voxel-based morphometry and gyrification.
Brain Imaging Behav. 2021 15(5):2237-2245 PDF

Schmidt S, Gull S, Herrmann KH, Boehme M, Irintchev A, Urbach A, Reichenbach JR, Klingner CM, Gaser C, Witte OW.
Experience-dependent structural plasticity in the adult brain: How the learning brain grows.
Neuroimage 2021 225:117502 PDF

Kurth F, Gaser C, Luders E.
Development of sex differences in the human brain.
Cogn Neurosci. 2021 12(3-4):155-162 PDF

Vickery S, Hopkins WD, Sherwood CC, Schapiro SJ, Latzman RD, Caspers S, Gaser C, Eickhoff SB, Dahnke R, Hoffstaedter F.
Chimpanzee brain morphometry utilizing standardized MRI preprocessing and macroanatomical annotations.
Elife 2020 9:e60136 PDF

Franke K, Bublak P, Hoyer D, Billiet T, Gaser C, Witte OW, Schwab M.
In vivo biomarkers of structural and functional brain development and aging in humans.
Neurosci Biobehav Rev. 2020 117:142-164 PDF

Schmitz-Koep B, Bäuml JG, Menegaux A, Nuttall R, Zimmermann J, Schneider SC, Daamen M, Scheef L, Boecker H, Zimmer C, Gaser C, Wolke D, Bartmann P, Sorg C, Hedderich DM.
Decreased cortical thickness mediates the relationship between premature birth and cognitive performance in adulthood.
Hum Brain Mapp. 2020 41(17):4952-4963 PDF

Evermann U, Gaser C, Besteher B, Langbein K, Nenadic I.
Cortical Gyrification, Psychotic-Like Experiences, and Cognitive Performance in Nonclinical Subjects.
Schizophr Bull. 2020 46(6):1524-1534 PDF

Seidel G, Gaser C, Götz T, Günther A, Hamzei F.
Accelerated brain ageing in sepsis survivors with cognitive long-term impairment.
Eur J Neurosci. 2020 52(10):4395-4402 PDF

Kharabian Masouleh S, Eickhoff SB, Zeighami Y, Lewis LB, Dahnke R, Gaser C, Chouinard-Decorte F, Lepage C, Scholtens LH, Hoffstaedter F, Glahn DC, Blangero J, Evans AC, Genon S, Valk SL.
Influence of Processing Pipeline on Cortical Thickness Measurement.
Cereb Cortex. 2020 30(9):5014-5027 PDF

Engl C, Tiemann L, Grahl S, Bussas M, Schmidt P, Pongratz V, Berthele A, Beer A, Gaser C, Kirschke JS, Zimmer C, Hemmer B, Mühlau M.
Cognitive Impairment in Early MS: Contribution of White Matter Lesions, Deep Grey Matter Atrophy, and Cortical Atrophy.
J Neurol. 2020 267(8):2307-2318 PDF

Luders E, Kurth F, Gingnell M, Engman J, Yong EL, Poromaa IS, Gaser C.
From baby brain to mommy brain: Widespread gray matter gain after giving birth.
Cortex. 2020 126, 334-342 PDF

Brodoehl S, Gaser C, Dahnke R, Witte OW, Klingner CM.
Surface-based analysis increases the specificity of cortical activation patterns and connectivity results.
Sci Rep. 2020 10 (1), 1-13 PDF

Nenadic I, Voss A, Besteher B, Langbein K, Gaser C.
Brain structure and symptom dimensions in borderline personality disorder.
Eur Psychiatry. 2020 63(1):e9 PDF

Steinbach R, Batyrbekova M, Gaur N, Voss A, Stubendorff B, Mayer TE, Gaser C, Witte OW, Prell T, Grosskreutz J.
Applying the D50 disease progression model to gray and white matter pathology in amyotrophic lateral sclerosis.
NeuroImage: Clin. 2020 25, 102094 PDF

Hedderich DM, Bäuml JG, Menegaux A, Avram M, Daamen M, Zimmer C, Bartmann P, Scheef L, Boecker H, Wolke D, Gaser C, Sorg C.
An analysis of MRI derived cortical complexity in premature-born adults: Regional patterns, risk factors, and potential significance.
NeuroImage 2020 208, 116438 PDF

Pigdon L, Willmott C, Reilly S, Conti-Ramsden G, Gaser C, Connelly A, Morgan AT.
Grey matter volume in developmental speech and language disorder.
Brain Struct Funct. 2019 224(9), 3387-3398 PDF

Pongratz V, Schmidt P, Bussas M, Grahl S, Gaser C, Berthele A, Hoshi MM, Kirschke J, Zimmer C, Hemmer B, Mühlau M.
Prognostic value of white matter lesion shrinking in early multiple sclerosis: An intuitive or naïve notion?
Brain Behav. 2019 9(12), e01417 PDF

Besteher B, Gaser C, Ivanšic D, Guntinas-Lichius O, Dobel C, Nenadic I.
Chronic tinnitus and the limbic system: Reappraising brain structural effects of distress and affective symptoms.
NeuroImage: Clin. 2019 24, 101976 PDF

Franke K, Gaser C.
Ten years of BrainAGE as a neuroimaging biomarker of brain aging: What insights have we gained?
Front Neurol. 2019 10, 789 PDF

Spalthoff R, Degenhardt F, Awasthi S, Heilmann-Heimbach S, Besteher B, Gaser C, Ripke S, Nöthen MM, Nenadic I.
Effects of a neurodevelopmental genes based polygenic risk score for schizophrenia and single gene variants on brain structure in non-clinical subjects: A preliminary report.
Schizophr Res. 2019 212, 225-228 PDF

Besteher B, Squarcina L, Spalthoff R, Bellani M, Gaser C, Brambilla P, Nenadic I.
Hippocampal Volume as a Putative Marker of Resilience or Compensation to Minor Depressive Symptoms in a Nonclinical Sample.
Front Psychiatry. 2019 10, 467 PDF

Besteher B, Gaser C, Nenadic I.
Brain Structure and Subclinical Symptoms: A Dimensional Perspective of Psychopathology in the Depression and Anxiety Spectrum.
Neuropsychobiology 2019 78 (3), 113-126 PDF

Besteher B, Gaser C, Nenadic I.
Machine-learning based brain age estimation in major depression showing no evidence of accelerated aging.
Psychiatry Res Neuroimaging 2019 290, 1-4 PDF

Schmidt P, Pongratz V, Küster P, Meier D, Wuerfel J, Lukas C, Bellenberg B, Zipp F, Groppa S, Sämann PG, Weber F, Gaser C, Franke T, Bussas M, Kirschke J, Zimmer C, Hemmer B, Mühlau M.
Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging.
NeuroImage: Clin. 2019 23, 101849 PDF

Besteher B, Gaser C, Nenadic I.
Brain structure and trait impulsivity: A comparative VBM study contrasting neural correlates of traditional and alternative concepts in healthy subjects.
Neuropsychologia. 2019 131, 139-147 PDF

Hedderich DM, Bäuml JG, Berndt MT, Menegaux A, Scheef L, Daamen M, Zimmer C, Bartmann P, Boecker H, Wolke D, Gaser C, Sorg C.
Aberrant gyrification contributes to the link between gestational age and adult IQ after premature birth.
Brain. 2019 142 (5), 1255-1269 PDF

Lotze M, Domin M, Gerlach FH, Gaser C, Lueders E, Schmidt CO, Neumann N.
Novel findings from 2,838 adult brains on sex differences in gray matter brain volume.
Sci Rep. 2019 9 (1), 1-7 PDF

Eyme KM, Domin M, Gerlach FH, Hosten N, Schmidt CO, Gaser C, Flöel A, Lotze M.
Physically active life style is associated with increased grey matter brain volume in a medial parieto-frontal network.
Behav Brain Res. 2019 359, 215-222 PDF

Besteher B, Squarcina L, Spalthoff R, Bellani M, Gaser C, Nenadic I, Brambilla P.
Subclinical agoraphobia symptoms and regional brain volumes in non-clinical subjects: between compensation and resilience?
Front Psychiatry. 2018 9, 541 PDF

Spalthoff R, Gaser C, Nenadic I.
Altered gyrification in schizophrenia and its relation to other morphometric markers.
Schizophr Res. 2018 202:195-202 PDF

Luders E, Gingnell M, Poromaa IS, Engman J, Kurth F, Gaser C.
Potential Brain Age Reversal after Pregnancy: Younger Brains at 4-6 Weeks Postpartum.
Neuroscience 2018 386: 309-314 PDF

Scheller E, Schumacher LV, Peter J, Lahr J, Wehrle J, Kaller CP, Gaser C, Klöppel S.
Brain Aging and APOE e4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults.
Front Aging Neurosci. 2018 10: 74 PDF

Langbein K, Hesse J, Gussew A, Milleit B, Lavoie S, Amminger GP, Gaser C, Wagner G, Reichenbach JR, Hipler UC, Winter D, Smesny S.
Disturbed glutathione antioxidative defense is associated with structural brain changes in neuroleptic-naïve first-episode psychosis patients.
Prostaglandins Leukot Essent Fatty Acids 2018 136:103-110 PDF

Franke K, Gaser C, Roseboom TJ, Schwab M, de Rooij SR.
Premature brain aging in humans exposed to maternal nutrient restriction during early gestation.
Neuroimage. 2018 173:460-471 PDF

Rogenmoser L, Kernbach J, Schlaug G, Gaser C.
Keeping brains young with making music.
Brain Struct Funct. 2018 223(1):297-305 PDF

Maggioni E, Crespo-Facorro B, Nenadic I, Benedetti F, Gaser C, Sauer H, Roiz-Santiañez R, Poletti S, Marinelli V, Bellani M, Perlini C, Ruggeri M, Altamura AC, Diwadkar VA, Brambilla P; ENPACT group.
Common and distinct structural features of schizophrenia and bipolar disorder: The European Network on Psychosis, Affective disorders and Cognitive Trajectory (ENPACT) study.
PLoS ONE. 2017 12(11): e0188000 PDF

Besteher B, Squarcina L, Spalthoff R, Bellani M, Gaser C, Brambilla P, Nenadic I.
Brain structural correlates of irritability: Findings in a large healthy cohort.
Hum Brain Mapp. 2017 38(12): 6230-6238 PDF

Steinke J, Gaser C, Langbein K, Dietzek M, Gussew A, Reichenbach JR, Smesny S, Sauer H, Nenadic I.
Hippocampal metabolism and prefrontal brain structure: a combined 1H-MR spectroscopy, neuropsychological, and voxel-based morphometry (VBM) study.
Brain Res. 2017 1677: 14-10 PDF

Besteher B, Gaser C, Spalthoff R, Nenadic I.
Associations between urban upbringing and cortical thickness and gyrification.
J Psychiatr Res. 2017 95: 114-120 PDF

Righart R, Schmidt P, Dahnke R, Biberacher V, Beer A, Buck D, Hemmer B, Kirschke JS, Zimmer C, Gaser C, Mühlau M.
Volume versus surface-based cortical thickness measurements: A comparative study with healthy controls and multiple sclerosis patients.
Brain Struct Funct. 2017 12(7): e0179590 PDF

Nenadic I, Dietzek M, Langbein K, Sauer H, Gaser C.
BrainAGE score indicates accelerated brain aging in schizophrenia, but not bipolar disorder.
Psychiatry Res. 2017 266: 86-89 PDF

Franke K, Clarke GD, Dahnke R, Gaser C, Kuo AH, Li C, Schwab M, Nathanielsz PW.
Premature Brain Aging in Baboons Resulting from Moderate Fetal Undernutrition.
Front Aging Neurosci. 2017 9: 92 PDF

Nenadic I, Yotter RA, Dietzek M, Langbein K, Sauer H, Gaser C.
Cortical complexity in bipolar disorder applying a spherical harmonics approach.
Psychiatry Res. 2017 263: 44-47 PDF

Besteher B, Gaser C, Langbein K, Dietzek M, Sauer H, Nenadic I.
Effects of subclinical depression, anxiety and somatization on brain structure in healthy subjects.
J Affect Disord. 2017 215: 111-117 PDF